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The extracellular matrix can influence the shape of a cell because: (1) cell adhesion proteins on the plasma membrane attach to the extracellular matrix; (2) cell adhesion proteins attach to the cell's cytoskeleton; (3) the cytoskeleton determines cell shape.


A) Statement (1) is correct.
B) Statement (2) is correct.
C) Statement (3) is correct.
D) Statement (1) and (2) are correct.
E) All of the statements are correct.

F) A) and C)
G) B) and D)

Correct Answer

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E

The basal lamina:


A) is a specialized extracellular matrix found beneath epithelial tissues.
B) is found on top of the epidermis of the skin.
C) is a cell-rich layer.
D) links to epithelial cells through tight junctions.
E) All of these choices are correct.

F) C) and D)
G) A) and B)

Correct Answer

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Some cytoskeletal elements are more permanent than others. Which components of the cytoskeleton are dynamic structures?


A) microtubules
B) microfilaments
C) intermediate filaments
D) both microtubules and intermediate filaments
E) both microtubules and microfilaments

F) A) and C)
G) A) and B)

Correct Answer

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Which of the following cell junctions is involved in creating a barrier between cells?


A) desmosome
B) tight junction
C) adherens junction

D) All of the above
E) B) and C)

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A pathologist is carrying out an autopsy. Upon opening the chest cavity, the pathologist sees a thick, fibrous tissue surrounding the heart. This is likely:


A) neural tissue.
B) epithelial tissue.
C) muscle tissue.
D) connective tissue.

E) None of the above
F) C) and D)

Correct Answer

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Which one of the following properly groups a cell junction with a cytoskeletal element and a cell adhesion molecule?


A) adherens junction, microfilament, integrin
B) hemidesmosome, microfilament, cadherin
C) desmosome, intermediate filament, cadherin
D) hemidesmosome, intermediate filament, cadherin

E) All of the above
F) A) and D)

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How does the extracellular matrix affect a cell that it surrounds?


A) The cell's shape depends in part on the structure and composition of the extracellular matrix.
B) The genes that the cell expresses depend in part on the types of proteins in the extracellular matrix.
C) The size that the cell grows to depends in part on the polysaccharides in the extracellular matrix.
D) The extracellular matrix has no effect on the cells that it surrounds.
E) All of these choices are correct.

F) A) and E)
G) A) and B)

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Epidermolysis bullosa is a set of rare genetic disorders that is caused by:


A) a keratin gene that disrupts intermediate filaments, weakening epidermal cell connections.
B) a microfilament gene that disrupts desmosomes, weakening epidermal cell connections.
C) an intermediate filament gene that disrupts hemidesmosomes, weakening epidermal cell connections.
D) a keratin gene that disrupts microfilaments, weakening epidermal cell connections.
E) All of these choices are correct.

F) C) and D)
G) B) and C)

Correct Answer

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Which motor protein(s) would you find in a flagellum?


A) myosin
B) dynein
C) kinesin
D) both myosin and dynein

E) A) and D)
F) A) and B)

Correct Answer

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Dynein is a motor protein found attached to:


A) lamin.
B) microfilaments.
C) microtubules.
D) intermediate filaments.

E) B) and C)
F) A) and D)

Correct Answer

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C

The natural loss of dead cells from the surface of your skin is a result of:


A) loss of adherens junctions between epithelial cells.
B) breakdown of desmosomes.
C) loss of microvilli.
D) both the loss of adherens junctions between epithelial cells, and the breakdown of desmosomes.

E) A) and B)
F) A) and C)

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Gap junctions and plasmodesmata have what feature in common?


A) They both allow direct transport of materials between cells.
B) They both are made up of protein subunits located in the plasma membrane.
C) They are both found in plant cells.
D) They both attach to the cytoskeleton.

E) C) and D)
F) B) and D)

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How do cells connect to the extracellular matrix?


A) through cadherins
B) through integrins
C) through gap junctions
D) through tight junctions

E) B) and D)
F) A) and C)

Correct Answer

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Dynamic instability is a:


A) feature of microtubules.
B) feature of microfilaments.
C) feature of intermediate filaments.
D) feature of microtubules and microfilaments.
E) universal feature of the cytoskeleton.

F) A) and E)
G) B) and E)

Correct Answer

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Which of the following is a component of the extracellular matrix made by a plant cell?


A) collagen
B) cadherin
C) cellulose
D) All of these choices are correct.

E) A) and B)
F) None of the above

Correct Answer

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The classic experiment using isolated cells from two species of sponges provided evidence that:


A) cell adhesion molecules are species specific.
B) sponge cells possess an extracellular matrix.
C) cell adhesion molecules are nonspecific.
D) sponge cells have cell adhesion molecules.

E) B) and C)
F) A) and D)

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Kinesin is a motor protein found attached to:


A) microfilaments.
B) microtubules.
C) intermediate filaments.
D) tubulin.

E) A) and D)
F) A) and B)

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The internal cytoskeletal structure of cilia and flagella grows out from a structure called a basal body located near the cell surface. Based on this information, where would you predict the plus end of the microtubules to be located?


A) near the basal body
B) near the tip of the cilia or flagella
C) at both ends of the cilia or flagella
D) It is not possible to predict from the information provided.

E) A) and B)
F) A) and C)

Correct Answer

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Within the plant cell wall, the primary cell wall contains _____, and the secondary cell wall is composed of _____.


A) only cellulose; only lignin
B) only lignin; only cellulose
C) both pectin and cellulose; both lignin and cellulose
D) both lignin and cellulose; pectin and cellulose
E) only pectin; only lignin

F) A) and C)
G) C) and D)

Correct Answer

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Intermediate filaments:


A) have a diameter that is larger than a microfilament, but smaller than a microtubule.
B) play an important role in maintaining cell shape.
C) play an important role in preventing skin from tearing by shear stress.
D) undergo little change in length in comparison to microtubules and microfilaments.
E) All of these choices are correct.

F) B) and C)
G) C) and D)

Correct Answer

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E

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