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A child is born with a congenital disease that results in total loss of B cells. Which of the following would be a consequence of this immunodeficiency?


A) no lymphokine production
B) lack of antibody formation
C) nonfunctioning complement system
D) inability to form any type of memory cell
E) no antigens on the cells

F) None of the above
G) B) and E)

Correct Answer

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Several days after an initial contact with an antigen, antibody blood levels increases. This is a


A) primer response.
B) primary response.
C) precipitating response.
D) principle response.
E) cascade response.

F) A) and E)
G) A) and B)

Correct Answer

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Match the appropriate characteristic with the type of immunity. -memory cells


A) innate immunity
B) antibody-mediated immunity
C) cell-mediated immunity
D) both antibody and cell-mediated immunity
E) innate immunity, antibody-mediated immunity and cell-mediated immunity

F) C) and D)
G) A) and D)

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Which of the following statements accurately describes the thymus gland?


A) The thymus gland lacks a capsule.
B) The thymus gland contains many reticular fibers.
C) The thymus gland decreases in size after age 60.
D) Lymphocytes are found only in the medulla of the thymus gland.
E) The thymus increases in size with aging.

F) All of the above
G) C) and D)

Correct Answer

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Cytotoxic T cells


A) produce antibodies for general circulation.
B) attach to the surface of cells causing them to lyse.
C) cause precipitation of antigens.
D) have IgG antibodies on their cell membranes.
E) are destroyed after contact killing.

F) A) and B)
G) C) and E)

Correct Answer

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During the inflammatory response,


A) vasoconstriction occurs.
B) chemical mediators are released.
C) vascular permeability is decreased.
D) neutrophil production is depressed.
E) blood flow is reduced.

F) B) and E)
G) C) and D)

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Match the term with the appropriate description. -histamine


A) lipids that cause smooth muscle relaxation and vasodilation
B) lymph nodules aggregated in the small intestinal wall
C) rounded epithelial structures found in the medulla of thymus
D) areas of a lymph node where lymphocytes divide
E) a chemical released from mast cells that causes vasodilation

F) A) and E)
G) C) and E)

Correct Answer

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Stimulating the proliferation of cytotoxic T cells to destroy cancer cells is an example of


A) immunotherapy.
B) immunocompetence.
C) tolerance.
D) passive artificial acquired immunity.
E) passive natural acquired immunity.

F) A) and B)
G) A) and C)

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Which is the proper order of events in cell-mediated immunity? (1) cloning of cytotoxic T cells and memory T cells (2) antigen presented to T lymphocyte (3) activation of T lymphocytes (4) cytotoxic T cells attack target cells


A) 2, 3, 4, 1
B) 1, 4, 2, 3
C) 2, 3, 1, 4
D) 3, 2, 4, 1
E) 1, 2, 3, 4,

F) A) and B)
G) A) and C)

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Nonencapsulated lymphatic tissue called MALT includes all of the following except:


A) tonsils.
B) Peyer patches.
C) lymph nodes.
D) diffuse lymphatic tissue.

E) None of the above
F) A) and B)

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Lymphocyte activation can occur in several ways. However, in all cases


A) lymphocytes must recognize an antigen.
B) helper T cells are activated first and they then stimulate other cells.
C) antigen-presenting cells process the antigen and present it to the lymphocytes.
D) cytokines released by the antigen stimulate the lymphocyte response.
E) antigens must be able to recognize the lymphocytes.

F) B) and C)
G) A) and D)

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An MHC class II/antigen complex on the surface of an antigen-presenting cell (APC) binds to a T-cell receptor. What results from this interaction?


A) Other immune cells are inhibited
B) The antigen is phagocytized by the T cell
C) The T cell responds by directly destroying the APC
D) Other immune cells are stimulated to respond to the antigen

E) B) and D)
F) None of the above

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During the development of lymphocytes, some pre-T and pre-B cells survive and develop into cells capable of an immune response, this is referred to as ______ selection. However some cells are suppressed from responding to self antigens, this is referred to as ______ selection.


A) negative; positive
B) neutral; negative
C) negative; neutral
D) neutral; positive
E) positive; negative

F) A) and E)
G) A) and D)

Correct Answer

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What is the function of thymosin?


A) destroys damaged red blood cells
B) destroys damaged white blood cells
C) activates lymphocytes in lymph nodes
D) maturation of T-cells

E) A) and B)
F) C) and D)

Correct Answer

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A surface chemical that prevents microbial growth is


A) histamine.
B) leukotriene.
C) sebum.
D) kinin.
E) interferon.

F) A) and B)
G) A) and C)

Correct Answer

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Which of the following is usually the first cell type to leave the blood and enter infected tissues?


A) eosinophil
B) lymphocyte
C) monocyte
D) natural killer cell
E) neutrophil

F) A) and E)
G) B) and D)

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E

Lymph capillaries are found in the


A) epidermis.
B) cornea.
C) bone marrow.
D) central nervous system.
E) dermis.

F) A) and B)
G) C) and D)

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Defense mechanisms that respond at the same speed and efficiency upon repeated exposure are classified as ______ immunity and defense mechanisms that increase in speed and strength upon repeated exposure are classified as ______ immunity.


A) innate; non-specific
B) adaptive; innate
C) specific; innate
D) innate; adaptive

E) A) and B)
F) All of the above

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D

Match the appropriate characteristic with the type of immunity. -tears and saliva


A) innate immunity
B) antibody-mediated immunity
C) cell-mediated immunity
D) both antibody and cell-mediated immunity
E) innate immunity, antibody-mediated immunity and cell-mediated immunity

F) B) and E)
G) All of the above

Correct Answer

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The process of eliminating those lymphocytes that react or respond against self-antigens is called


A) phagocytosis.
B) inflammation.
C) negative selection.
D) activation of complement.
E) natural selection.

F) A) and D)
G) C) and D)

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C

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