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Tolerance to antigens is induced by ________.


A) blocking costimulation
B) stimulating interleukin 2 production
C) preventing suppressor T cell proliferation
D) promoting the release of cytokines
E) stimulating helper T cell division

F) B) and D)
G) A) and B)

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Artificially stimulating the proliferation of cytotoxic T cells to destroy cancer cells is an example of ________.


A) immunotherapy
B) immunocompetence
C) tolerance
D) passive artificial acquired immunity
E) passive natural acquired immunity

F) B) and C)
G) C) and D)

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Match the type of cell with its function. -Natural killer cell


A) First cell to enter infected tissue
B) Will become macrophage in tissue
C) Lyses tumor and virus-infected cells
D) Cell that increases in number during a parasitic infection
E) Nonmotile cells in connective tissue that promote inflammation

F) A) and D)
G) D) and E)

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The effects of cell-mediated immunity are the result of activities of ________.


A) B cells
B) cytotoxic T cells
C) macrophages
D) dendritic cells
E) helper T cells

F) B) and C)
G) D) and E)

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The white pulp of the spleen


A) contains lymphocytes that can stimulate an immune response.
B) filters lymph as it flows through the spleen.
C) destroys defective red blood cells.
D) All of the choices are correct.

E) None of the above
F) All of the above

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The redness and heat seen in an inflamed area are the result of


A) vasoconstriction.
B) increased blood flow to the area.
C) phagocyte mobilization.
D) production of interferon.
E) a reddish substance released by erythrocytes.

F) C) and D)
G) A) and D)

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The palatine tonsils


A) interfere with breathing when enlarged.
B) are located at the junction of the oral cavity and pharynx.
C) are located superior to the palate.
D) are really lymph nodes in disguise.
E) are located in the nasopharynx.

F) A) and B)
G) A) and C)

Correct Answer

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Which is the correct sequence of events in the humoral immune response?


A) Antigen recognition → antigen presentation → differentiation → clonal selection → attack
B) Antigen recognition → antigen presentation → clonal selection → differentiation → attack
C) Antigen presentation → antigen recognition → clonal selection → differentiation → attack
D) Antigen presentation → antigen recognition → clonal selection → attack differentiation
E) Antigen recognition → differentiation → antigen presentation → clonal selection → attack

F) C) and D)
G) None of the above

Correct Answer

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The lymphatic system differs from the cardiovascular system in that


A) the lymphatic system only carries fluid away from tissues.
B) the lymphatic vessels have their own "pump" to assist flow.
C) lymph capillaries do not contain any fluid.
D) lymph capillaries allow free movement of fluid in and out of the capillaries.
E) lymph circulates fluids and cardiovascular does not.

F) All of the above
G) A) and B)

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Structurally, lymph vessels are most similar to ________.


A) veins
B) arteries
C) arterioles
D) capillaries
E) venules

F) None of the above
G) C) and D)

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Jared received a donor kidney. After the first week, it became apparent that Jared's body was rejecting the organ. This is due to


A) a lack of a match between Jared's immune cells and the MHC class I molecules on the cells of the donor kidney.
B) Jared's lack of helper T cells that prevent the lymphatic tissue of the donated kidney damaging the donated kidney.
C) an autoimmune disease that is destroying healthy tissue.

D) All of the above
E) None of the above

Correct Answer

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Different T-cell receptors can respond to different antigens because of different


A) variable regions in the structure of the receptors.
B) epitopes in the receptor's structure.
C) selection processes.
D) complement binding sites in the receptors.
E) antigenic determinants.

F) B) and E)
G) C) and E)

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Lymph from which of the following area of the body will pass through the thoracic duct before entering the bloodstream?


A) Right hip
B) Right ring finger
C) Right shoulder
D) None of the choices are correct.

E) B) and D)
F) C) and D)

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Which of the following is correctly matched?


A) IgA - found in saliva and tears
B) IgD - can cross the placenta
C) IgG - first to challenge the antigen
D) IgM - antigen-binding receptor on B cells
E) IgE - transfusion reactions

F) B) and D)
G) A) and B)

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Inflammation of the inguinal lymph nodes is an indication of possible infection in the ________.


A) lower limb
B) reproductive organs
C) abdomen
D) upper limb

E) A) and C)
F) A) and D)

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The organs of the lymphatic system include lymph nodes, the spleen, and the thyroid gland.

A) True
B) False

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The introduction of antibodies from another source will stimulate the production of antibodies by the body.

A) True
B) False

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T helper cells possess a glycoprotein called CD4. This molecule binds to ________.


A) MHC class I molecules
B) MHC class II molecules
C) MHC-CD8 antigens
D) MHC-CD28 antigens
E) Interleukin-1 receptor

F) C) and D)
G) C) and E)

Correct Answer

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Antibodies are produced by


A) cytotoxic T cells stimulated by helper T cells.
B) helper T cells stimulated by various cytokines.
C) B cells that differentiate to form plasma cells.
D) natural killer cells as they lyse cancer cells.
E) the red bone marrow.

F) None of the above
G) A) and B)

Correct Answer

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Which of the following is usually the first cell type to leave the blood and enter infected tissues?


A) Eosinophil
B) Lymphocyte
C) Monocyte
D) Natural killer cell
E) Neutrophil

F) A) and D)
G) A) and C)

Correct Answer

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